Born 1927, Tel Aviv;
Ph.D. 1958, Hebrew Univ.;
Sen. Lect. 1966;
Assoc. Prof. 1970;
Member of the Editorial l Board of Inflammopharmacology
Mechanisms of cell and tissue injury in inflammatory and infectious conditions. Synergistic mechanisms among reactive oxygen and nitrogen species , proteolytic enzymes, membrane-perforating agents and cytokines on cells in vitro and in vivo. Mechanism of bacteriolysis induced by cationic peptides, cationic proteins and enzymes and by antibiotics and its regulations by polysulfates and by non-bacteriolytic antibiotics. The role of lipoteichoic acid (LTA) from Gram-positive bacteria as modulators of inflammatory processes. The role of the Tibetan plant mixtures PADMA-28 and PADMA-Q as sources for anti-oxidants, anti-proteinases, anti-cytokines and as modulators of inflammatory processes and of experimental autoimmune phenomena, such as diabetes, lupus, sepsis, septic shock and multiple organ failure.
The role of food - derived polyphenols as anti oxidant agents .
Interactions and binding of polyphenols to microbial cells converting them to potent anti oxidant entities
The role of red blood cells as protectors of cells against oxidative stresses induced by reactive oxygen species
The role of Tibetan plants as modulators of type 1 diabetes in NOD mice ( Collaboration with Dr. Lola Weiss , Hadassah hospital
Healing of skin wounds in diabetic rats by extracts from Tibetan plants ( Collaboration with the Dept. Pathology, University of Michigan USA )
Suppression of liver cirrhosis in mice by Indian plant extracts ( collaboration with Dr. R. Safadi, Liver Unit, Hadassah Hospital