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Researchers
  • Dr.  David Polak
 
Personal details
Date of birth: July 20, 1975
Family status: Married, + 3 children
Work phone: 972-2-6776742
Fax: 972-2-6429683
E-mail: polak@mail.huji.ac.il
 
Educational background
2006 – 2010, Hebrew University - Hadassah medical center, Post-graduate in periodontology                                 
2004 – 2010, Hebrew University - Hadassah medical center, immunology, Ph.D., " Pathogenesis of poly-microbial experimental periodontitis in mice using a model of mixed infection with P. gingivalis and F. nucleatum" supervisors: Prof. Lior Shapira and Dr. Yael Houri-Haddad.  #4,6,8                                                                                                                          
2002 – 2004, Hebrew University - Hadassah medical center,  immunology , M.Sc., " Inflammatory response to mixed infection with P. gingivalis and F. nucleatum", supervisors: Prof. Lior Shapira, Prof. Ervin Weiss and Dr. Yael Huori-Haddad. 
 
2001 – 2004, Hebrew University - Hadassah medical center, Dentistry, D.M.D.                                                                                      
1998 - 2001 Hebrew University - Hadassah medical center, Dentistry, B.Med.Sc.(with distinction)     .                                                                                              
 
Appointments at the Hebrew University
 
2012- Today, Course supervisor – course no. 97877, dental faculty, Periodontology.
 
2008-today, Introduction to Periodontology - 4th year DMD studies, 3 academic lectures
 
2006-today, Adult integrated treatment – Periodontology - 5th year DMD studies, Clinical instructor and 3 academic lectures
 
 
Research activity
 
Pathogenesis of periodontal disease in a murine model
Interaction between oral epithelium and periodontal pathogens
Chronic inflammation and immunological tolerance
List of publication
Polak D, Shapira L, Weiss EI, and Houri-Haddad Y. Virulence mechanism of bacteria in mixed infection:  Attenuation of cytokine Levels and evasion of PMN phagocytosis. J Periodontol. Accepted for publication.  
Polak D, Nadaf R, Shapira L, Weiss EI, and Houri-Haddad Y. The protective potential of non-dialysable material fraction of cranberry juice on the virulence of P. gingivalis and F. nucleatum mixed infection. J Periodontol. 2012, In press.
Abramovitz I, Beyth N,Weinberg G, Borenstein A, Polak D, Kesler-Shvero D, and Houri-Haddad Y.In Vitro Biocompatibility of Endodontic Sealers Incorporating Antibacterial Nanoparticles. J Nanomaterials. 2012, 9.
Polak D, Shapira L, Weiss EI, Houri-Haddad Y. The role of coaggregation between Porphyromonas gingivalis and Fusobacterium nucleatum on the host response to mixed infection. J Clin Periodontol. 2012 Jul; 39(7):617-25. 
Chaushu S, Wilensky A, Gur C, Shapira L, Elboim M, Halftek G, Polak D, Achdout H, Bachrach G, Mandelboim O.Direct recognition of Fusobacterium nucleatum by the NK cell natural cytotoxicity receptor NKp46 aggravates periodontal disease. PLoS  Pathog. 2012; 8(3).
Polak D, Wilensky A, Shapira L, Weiss EI, Houri-Haddad Y. Vaccination of mice with Porphyromonas gingivalis or Fusobacterium nucleatum modulates the inflammatory response, but fails to prevent experimental periodontitis. J Clin Periodontol. 2010 Sep; 37(9):812-7. (Jaccard competition finalist).
Wilensky A*, Polak D*, Awawdi S, Halabi A, Shapira L, Houri-Haddad Y. Strain-dependent activation of the mouse immune response is correlated with Porphyromonas gingivalis-induced experimental periodontitis. J Clin Periodontol. 2009 Nov; 36(11):915-21. *Equal contribution. (published with editorial).
Polak D, Wilensky A, Shapira L, Halabi A, Goldstein D, Weiss EI, Houri-Haddad Y. Mouse model of experimental periodontitis induced by Porphyromonas gingivalis/Fusobacterium nucleatum infection: bone loss and host response. J Clin Periodontol. 2009 May; 36(5):406-10. (published with editorial).
 
 
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