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  • Dr.  Iris Slutzky-Goldberg
Born, Israel 1961
B.Med.Sc.   1982 ,  Hebrew University-Hadassah, Jerusalem, ISRAEL
D.M.D.        1985,   Hebrew University-Hadassah, Jerusalem, ISRAEL
Specialist in Endodontics   2001.  Hebrew University-Hadassah, Jerusalem, ISRAEL
Clinical lecturer.  2007
Hebrew University-Hadassah, Jerusalem, ISRAEL
Director of post graduate program in endodontics, Department of Endodontics, Hebrew University-Hadassah, Jerusalem, ISRAEL 2008

Awards and Grants :
·         1999    Best postgraduate student in Endodontics.
·         2000    Dean's list for best teachers, Hebrew University-Hadassah School of Dental Medicine
·         2006    Dean's list for best teachers, Hebrew University-Hadassah School of Dental Medicine
·         2007 - The joint research fund of the Hebrew University and Hadassah:
·         2008- The Ralph and Bette Rothstein –Antibacterial Properties of 4  Endodontic Cements
·         2010    Dean's list for best teachers, Hebrew University-Hadassah School of Dental Medicine
·         2011- The Ernst and Tova Turnheim (Nee Alexandrovitz) Clinical Research Fund in Dentistry – Changes in dentin microhardness after exposure to MTA for different time periods. Dr. Shlomo Matalon & Dr. Iris Slutzky- Goldberg
·         2012- The Meveline Lefko and Brown Sanford Fund - Potential applications of Pro-Argin in Root Canal Treatment
Research Interests:
  • Endodontic materials and techniques- Physical and mechanical aspects
  • Antibacterial properties of endodontic materials
  • The relationships between endodontics and systemic disease
  • Outcome of endodontically treated teeth- The restorative perspective


Research Projects:
·         Bacteria remaining in the root canal after biomechanical preparation and coronal leakage are considered to be possible factors effecting the outcome of endodontic disease. An antibacterial effect of the root filling materials or the temporary restorative materials may enable selectivity of the bacteria able to penetrate the root canal, but on the other hand can be advantageous in preventing repopulation of residual bacteria remaining in the root canals.
Our study is aimed at testing the antibacterial properties of different materials commonly used during endodontic treatment. Endodontic cements, such as AH-26, AH-plus, Roth sealer, etc. Core obturation materials like gutta perch and Resilon, and different temporary filling materials are tested for their ability to prevent bacterial growth in the root canal.  A quantitative test is performed using the Direct Contact Test (DCT). A qualitative morphological examination of the contaminated samples is carried out using a Scanning Electron Microscope (SEM). The materials are tested in different time periods, either fresh or aged when in contact with the bacteria. The bacterial properties are testes both aerobically and anaerobically. The bacteria tested for aerobic behavior is E.Faeclis, a bacteria associated with root treatment failures. Whereas, the anaerobic properties are tested when in contact with Actinomyces viscous and Prevotella Intermedia – which are involved with symptomatic apical periodontitis are tested.
·          Revascularization has been suggested for treatment of necrotic immature permanent teeth. The desirable outcome of the treatment is continuous growth of the root, maturation of the dentin walls and apical closure. It is usually attempted when the root is relatively very immature. Despite of increasing numbers of case reports, or case series - data lacks and a uniform treatment protocol has not been set.
In view of the fact that we are treating a large number of cases of immature teeth, we are currently evaluating the outcome of revascularization both radiographically and clinically, with a special emphasis on sensibility tests. We are also questioning the advantage of this procedure in trauma cases affecting incisors teeth, especially due to frequent discoloration of the teeth following revascularization.
·       The relationship of oral health to overall good health is indisputable. Many epidemiological studies have investigated the relationship between periodontal disease and cardiovascular disease, and in particular the association of periodontal infections as a risk factor for causing atherosclerosis and ischemic heart disease.  As apical periodontitis has long been associated with cholesteatomas, a study was carried out to assess the incidence of cholesterol clefts in biopsies obtained during apical surgery.  Higher incidence of cholesterol clefts were found in the elderly group suggesting a link between apical periodontitis and atherosclerosis. Currently under progress is a study aimed at demonstrating an association between apical periodontitis and general health, with a special emphasis on cardiovascular disease, using radiographic evaluation and patients' data.

Recent publications:
1.    Slutzky-Goldberg I. Apexification – calcium hydroxide and MTA in A. Moursi  Clinical Cases in Pediatric Dentistry,  Willey Blackwell,
2.    Tsesis I, Silvio Taschieri SC, Slutzky-Goldberg I. Contemporary Endodontic Treatment. International Journal of Dentistry 2012,  Article ID 23136
3.      Slutzky- Goldberg I, Slutzky H, Hanut A, Baev V,  Matalon S. The effect of dentin on the pulp tissue dissolution capacity of sodium hypochlorite and calcium hydroxide. Journal of Endodontics. 2013 Aug; 39(8):980-3.
4.      Slutzky- Goldberg I, Baev V, Volkov A, Zini A,  Tsesis I. Incidence of
cholesterol in Periapical Biopsies among Adolescent and Elderly Patients. Journal of Endodontics 2013 Dec; 39(12):1477-80.
5.     Slutzky-Goldberg I, Heling I. Revasculrization? Only as the last resort!
Refuat Hapeh Vehashinayim 2013, 30(3):30-5
6.       Slutzky- Goldberg I, Sabag L, Keinan DC. The influence of mineral trioxide aggregate (MTA) thickness on its microhardness properties — an in vitro study.  Enododontic practice 2014 March (Epub)
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